The mercurial nature of influenza has made this virus a formidable foe throughout the centuries. With its talent for mutation, close monitoring of influenza is critical to contain outbreaks of new strains. Over the past year, avian influenza, or “bird flu,” has been in the news. Let’s take a closer look at the history of avian influenza, the current status of H5N1 virus and what this may mean for the future.